The "vakgroep" (department) Analytische Scheikunde
en Farmaceutische Technologie (Analytical Chemistry and Pharmaceutical
Technology) is the result of a merger between the laboratory for
pharmaceutical and biomedical analysis (FABI) and the laboratory
The department is part of the Pharmaceutical School of the Faculty
of Medicine and Pharmacy of the Vrije Universiteit Brussel. It
is located in building G, ground floor of the campus Jette (see
location) of the university.
The main research topics are situated in chemometrics and separation
science. Chemometrics is defined as the chemical discipline that
uses mathematics, statistics and formal logic to design or select
optimal experimental procedures; to provide maximum relevant chemical
information by analyzing chemical data and to obtain knowledge
about chemical systems.
In Separation Science the main research goal is the evaluation
of "the rational use of new developments in separation techniques".
The separation techniques considered are liquid chromatography
(LC - UPLC), capillary electrophoresis (CE), capillary electrochromatography
(CEC) and supercritical fluid chromatography (SFC). Research is,
in a first instance performed on chiral separations, performed
by means of all above mentioned techniques. Further also chromatographic
fingerprint development for herbal extracts and their applications
are studied as well as drug impurity profiling by means of HPLC
and SFC. The fingerprint application can be considered for different
purposes, such as identification and QC, similarity analysis,
classification and calibration purposes. Their application usually
requires the use of multivariate data analysis techniques
The data analysis aspects of the research thus mainly are conducted on separation science data. They comprise, for instance, the use of experimental designs to optimize separations, and multivariate similarity analyses, unsupervised and supervised discrimination/classification approaches and calibration aspects on fingerprint data. Additionally, chemometric techniques are used to evaluate the (dis)similarity of different chiral separation systems as well as in the comparison of SFC systems and columns.
The department is also part of an alliance research group with the University of Ghent, more specifically with the PAT (Process Analytical Technologies) research group of T. De Beer. It is called PAT-Chemometrics and the VUB group is mainly involved in the data analysis aspects of the joint research.
Our main courses are analytical chemistry and food science for
students in pharmacy. A full description can be found here.
Course material is available on the Campus intranet (from outside
you need a password).
memory to Professor D.L. Massart we keep the link to his impressive curriculum
We apologize if some links don't work
or are missing.
Remarks can be sent to Katrien